BIOE 201    Biology for Engineers        (3-0-3)

Introduction to biology, chemical basis of life, biomolecules, cell structure and function, cell metabolism and energy transfer, DNA structure, replication, transcription and translation, cell division (mitosis and meiosis), patterns in inherited trait, human inheritance, and biotechnology.

Prerequisite: CHEM 101 Co requisite: BIOE 202

 

BIOE 202   Biology for Engineers Lab      (0-3-1)

Microscopy, homeostasis, macromolecules, structure and function of living cells, diffusion, osmosis and the functional of biological membranes, enzymes: catalysts of life, respiration: energy conversion, isolation, identification of nucleic acids (DNA, RNA), mitosis and cytokinesis, meiosis, heredity 1: Mendel’s Laws, heredity2: human inheritance.

Co-requisites: BIOE 201

BIOE 211   Fundamentals of Bioengineering   (3-0-3)

Cell content and architecture, cell physiology, genomics, proteomics, neural, endocrine and immunological control, stem cells therapy, drug delivery, engineering balances, basics in respiration, digestion, circulation and waste disposal, basics in biomechanics, bioinstrumentation, bioimaging, biomaterials, nanotechnology, tissue engineering and biomagnetism.

Prerequisite: BIOE 201, BIOE 202

BIOE 303   Cell Biology  (3-0-3)

Cell types and model organisms, structure and function of cell membrane, endomembrane systems and membrane trafficking, mitochondrion and chloroplast, cytoskeleton and cell signaling, cell junctions and extracellular matrix, cell cycle and cell death, stem cells and tissue renewal, cellular bioengineering applications.

Prerequisite: BIOE 201, CHEM 201

BIOE 311   Bioinstrumentation    (3-0-3)

Basic concepts of bioinstrumentation systems. Basic sensors and principles. Static and dynamic characteristics of measurement systems. Biomedical signal detection, amplification, and filtering. Biopotential electrodes. Biopotential amplifiers. Blood pressure, flow and volume of blood, respiratory systems, lab instrumentation, and Imaging systems. Biosensors. Electrical safety in the medical environment.

Prerequisite: BIOE 211, EE 236

BIOE 312   Bioinstrumentation lab   (0-3-1)

Blood Pressure Measurement, Echocardiography, Diathermy Equipment, ECG Wave Analysis, Patient Monitoring System, Ultrasound Blood Flow Measurement, Spirometry, Audiometer, PCG, Biotelemetry, Pacemaker Module, EMG Biofeedback with NCV.

Co requisite: BIOE 311

BIOE 316   Ethics and Safety in Bioengineering           (1-0-1)

Nature of bioethics, theories and framework for ethical analysis, bioethics and human futures, poverty, fertility, morality, genomics, eugenics and integrity, bioethics and animals, animals use for experiments, bioethics of plants and environment, genetically modified crops, dietary futures, environmental sustainability, bioethics in practice, risk, precaution, and trust, politics and biosciences, bioethics in the laboratory.

BIOE 320   Molecular Biology    (3-0-3)

DNA and chromosome structure, replication, recombination and transcription, RNA processing, translation, gene expression in prokaryotes and eukaryotes, gene mutation and DNA repair, genomics and proteomics, epigenetics, developmental genetics, immunogenetics, and cancer genetics, molecular bioengineering applications.

Prerequisite: BIOE 303, Co requisite: BIOE 321

BIOE 321   Cell and Molecular Biology Lab     (0-3-1)

Media preparation, bacterial cell culture and identification, prokaryote cell number, isolation of genomic DNA from bacteria, restriction enzyme digestion of DNA, ligation of plasmid DNA to insert DNA, transformation of E. coli by electroporation, polymerase chain reaction, agarose gel electrophoresis, total protein isolation, poly acrylamide gel electroporation.

Co requisite: BIOE 320

BIOE 337   Applied Physiology   (3-0-3)

Introduction to physiology, nervous, sensory, muscular, respiratory, renal, and cardiovascular systems, metabolic energy and homeostasis, blood flow regulation, digestive, endocrine, immune and reproductive systems, bioengineering applications of human physiology.

Prerequisite: BIOE 201

BIOE 355   Biomimicry Design and Modeling Lab        (0-3-1)

Introduction to biomimetics, complexity of biological systems and how the complexity can be mimicked to design novel materials, devices, and systems to solve important scientific challenges in bioengineering by applying different mathematical models to find solution of these problems using MATLAB program.

BIOE 370 Bioengineering Thermodynamics  (3-0-3)

Thermodynamics, First Law of Thermodynamics, Thermodynamic Properties, Control Volume Analysis, Second Law of Thermodynamics, Entropy, Exergy Analysis, Vapor and Gas Power Systems, Internal Combustion Engines, Refrigeration and Heat Pump Systems, Thermodynamic Relations, Reacting Mixtures and Combustion, Chemical and Phase Equilibrium.

Prerequisite: BIOE 211

BIOE 398 Internship    (0-0-6)*

A period of 16 weeks of industrial employment where bioengineering students work in appropriate industries or firms. Students are evaluated on their performance on the job and are required to submit an extensive formal report on their experience in addition to making a presentation before an examining committee.  

Prerequisites: BUS 200, ENGL 214, BIOE 320, BIOE 355

* To be eligible to register BIOE 398, the student should finish 85 credit hours.

BIOE 399   Summer Training   (0-0-1)

This course is limited to BIOE program. A continuous period of 8 weeks of summer training spent in the industry working in any of the fields of bioengineering. The training should be carried out in an organization with an interest in one or more of the BIOE fields. On completion of the program, the student is required to submit a formal written report of his work.

Prerequisite: ENGL 214, BIOE 320, BIOE 355

*To be eligible to register BIOE 399, the student should finish 65 credit hours.

BIOE 411 Senior Design Project I (0-1-0)

This is the first of two courses for the multidisciplinary, capstone project.  Multidisciplinary teams will be formed, projects will be defined, and project management discussed.

Prerequisite: BIOE 320, BIOE 355

BIOE 412 Senior Design Project II (0-6-3)

This is the second of two courses for the multidisciplinary, capstone project.  Multidisciplinary teams undertake product definition, generation of conceptual designs, product development, and presentation of final products.  Students integrate knowledge acquired from prior courses into multidisciplinary projects with multiple constraints and use engineering standards while further developing their communication skills and life-long learning techniques. The course enables the graduate to apply their bioengineering knowledge to solve real-life design problems or create and improve processes, devices, and systems to meet the demand of healthcare sector and medicine in the local and global context.

Prerequisite: BIOE 411

BIOE 434 Introduction to Biosensors (3-0-3)

Chemical Sensors and Biosensors, Materials and Methods in Biosensor Design, Affinity-Based Recognition, Enzymes and Enzymatic Sensors, Nucleic Acids in Chemical Sensors, Potentiometric Sensors, Amperometric Enzyme Sensors, Electrical-Impedance-Based Sensors, Optical Sensors Fundamentals, Nanomaterial Applications in Optical Transduction, Chemical Sensors Based on Microorganisms, Living Cells and Tissues.

Prerequisite: EE203, or EE 234, or EE 236, and CHEM 101

BIOE 440   Molecular Biotechnology   (3-0-3)

Molecular biotechnology, recombinant proteins production in prokaryotic hosts and eukaryotic cells, protein therapeutics, pharmaceuticals, enzymes, recombinant antibodies and vaccines, protein engineering and nucleic acids as therapeutic agents, industrial and environmental uses of recombinant microorganisms, transgenic plants and animals, molecular biotechnology, and society.

Prerequisite: BIOE 320

BIOE 445   Enzyme Engineering (3-0-3)

Concepts of protein and enzyme, biosynthesis of enzyme, production of enzyme, enzyme reactions kinetics, enzyme inhibition, enzyme immobilization, artificial enzymes, site-directed mutagenesis, application of enzyme engineering in the organic, biotechnology, pharmaceutical industries.

Prerequisite: Junior Standing

BIOE 455   Transport Phenomenon in Bioengineering (3-0-3)

Physiological Fluid Mechanics, Conservation and Momentum Balances, Fluid Transport, Dimensional Analysis and Scaling, Momentum Transport, Fluid Flow, Mass Transport, Diffusion, Transvascular Transport, Transport across the Kidney and Lungs, Ligand-Receptor Kinetics, Transport of Drugs and Heat Transfer in Biological Systems.

Prerequisite: BIOE 211

BIOE 460   Biomaterials   (3-0-3)

Biomaterials interaction with biological systems, properties of biomaterials used in medical applications, classes of biomaterials used in medicine, host reactions involved in biomaterials, biological testing of biomaterials, degradation of biomaterials in the biological systems, applications of biomaterials in medicine and artificial organs, tissue engineering.

BIOE 475   Cell Biology and Bioelectricity  (3-0-3)

Fundamentals of cell biology, biomolecules, cell structure and function, enzymes, biological redox chemistry and metabolism, respiration and photosynthesis, flow of genetic information from DNA to RNA to protein, bioelectric signals in the cell, Ion channels, membrane and action potential, brain, heart and neuro-muscular system physiology in relation with bioelectric signals and their propagation, sensory processes in animal involving stimuli, sensor-reception, electrical signal and brain processing, and examples of bioelectricity in other organisms.

Prerequisite: Senior Standing

BIOE 480   Biomechanics   (3-0-3)

Biomechanics, kinematic and kinetic concepts for analyzing human motion, biomechanics of human bone growth and development, biomechanics of human skeletal muscle, articulations and spine, linear and angular kinematics of human moment, and human movement in a fluid medium.

Prerequisite: BIOE 337, Senior Standing

BIOE 483 Genomics (3-0-3)

Genomes, transcriptomes, proteomes; genomes mapping, sequencing, annotation and identifying gene functions; eukaryotic, prokaryotes, virus genomes; accessing genome and DNA-protein interactions; recombination, transposition, mutations and DNA repair; genome evolution and comparative genomics.

Prerequisite: Junior Standing

BIOE 484 Introduction to Genetic Engineering   (3-0-3)

Basic molecular techniques, cutting and joining DNA, vectors and cloning strategies, analyzing cloned genes, cloning in bacteria and yeast, genetic manipulation of animal and plant cells, DNA libraries and sequencing strategies, omic tools for genes and protein functions.

BIOE 485   Electrophysiology    (3-0-3)

Biological redox chemistry, bioelectric signals in the cell, Ion channels, membrane and action potential, brain, heart, and neuro-muscular system physiology in relation with bioelectric signals and their propagation, sensory processes in animal involving stimuli, sensor-reception, electrical signal and brain processing, and examples of bioelectricity in other organisms.

BIOE 486   Nanobiotechnology   (3-0-3)

Nanobiotechnology, DNA and RNA nanostructures, aptamer-functionalized nanomaterials, artificial antibodies and enzymes, molecular motors, RNA nanomachines and virus-based nanotechnology, biosensors, nanobioprocessing, dielectrophoresis, nanofluidics, optical tweezers, nanotechnology for tissue engineering, drug delivery, siRNA Delivery and  nanotoxicity, release of bionanomaterials and future prospects of nanobiotechnology.

BIOE 487   Bioinformatics    (3-0-3)

Bioinformatics databases, next-generation sequencing, genome organization and evolution, archives and information retrieval, alignments and phylogenetic trees, structural bioinformatics and drug discovery, artificial intelligence and machine learning, systems biology, metabolic pathways, expression and regulation of gene regulatory networks, ethical apprehensions, and prospects of bioinformatics.

BIOE 488   Introduction to Modeling of Biological Systems    (3-0-3)

Discrete time models for population dynamics, linear difference equations. Use MATLAB to find the numerical solutions of the DE. Nonlinear discrete dynamical systems: graphical analysis, fixed points, linear stability analysis, chaotic dynamics, systems of difference equations. Some techniques for ordinary differential equations: equilibrium points, stability, linearization. Introduction to continuous dynamical systems: geometric (phase plane) analysis of 2-dim systems, linear systems.

BIOE 490  Special Topics in Bioengineering    (3-0-3)

Topics are selected from the broad area of Bioengineering to provide students with the knowledge of recent advancements in this area including but not limited to Biochemistry & Molecular Biology, Investigative Biology, Computational Molecular Biology, Genetics, Experimental Molecular Biology, Computational Human Genomics, Biological Circuit Engineering, Modeling Biomed. Systems, Drug Delivery, Translational Bioinformatics, Computational Intelligence for Biomedical Data, Biological Modeling: Mathematical and Computational Approaches, Biomedical Data Mining and Modeling.

Prerequisite: Senior Standing

BIOE 494  Undergraduate Thesis (I)    (0-0-3)

This course is an independent research course for students undertaking the CX in undergraduate research. An undergraduate thesis is a substantive piece of research-oriented creative work demonstrating mastery over the discourse of one semester in the professional bioengineering field. A thesis requires students to formulate the main hypothesis and research questions, maintain research integrity and be aware of research misconduct, and acquire skills to identify research gaps in literature. Students will develop their scientific writing skills to report their preliminary research findings in a research proposal.  Such a proposal must be planned and completed under the supervision of a faculty (advisor) and, at the advisor’s discretion and BIOE department approval, may be reviewed by an additional co-advisor. Student will have to present to a BIOE committee his/her research plan and hypothesis in the thesis proposal.  

Prerequisite: NA

BIOE 496  Undergraduate Thesis (II)    (0-0-3)

This is an independent research course focused on making research contributions and presenting the results in a thesis for students undertaking the CX in undergraduate research. In this course, students will refine their thesis proposal in previous thesis courses and work closely with the advisor to demonstrate their research findings over one semester in a professional bioengineering field. This requires students to ensure the novelty and originality of the idea, conduct extensive research in bioengineering to validate the main hypothesis and research questions and have the skills needed to write the thesis and prepare the research results for the proper venue for possible publication. Students will learn to develop their professional communication skills to defend their thesis in front of an independent BIOE scientific committee and possibly to deliver speeches in research symposia.

Prerequisite: Undergraduate Thesis (I) course