BIOE 501 Cellular and Molecular Bioengineering (3-0-3)
Cells and Genomes, Bioenergetics, Chromosomes, DNA Replication, Repair, and Recombination, Central Dogma, Control of Gene Expression, Recombinant DNA Technology, Membrane Transport, Intracellular Compartments, Protein Sorting and Membrane Traffic, Cell Signaling, Cell Junctions and Extracellular Matrix.
Prerequisite: Graduate Standing
BIOE 502 Anatomy and Physiology for Engineers (3-0-3)
Advanced concepts of animal physiology, including nervous, sensory, muscular, respiratory, renal, and cardiovascular systems, metabolic energy and homeostasis, digestive, endocrine, immune, and reproductive systems, and bioengineering applications of human physiology.
Prerequisite: Graduate Standing
BIOE 503 Concepts in Bioengineering (3-0-3)
Introduction to engineering calculations, conservation laws in biological systems, bioreactor configurations, drug delivery, stem cell and tissue engineering. Biomechanics, biomaterials, bioinstrumentation, bioimaging, biosignals, biosensors. Bioengineering ethics and entrepreneurship.
Prerequisite: Graduate Standing
BIOE 504 Statistics for Bioengineers (3-0-3)
Biostatistics, probability, distributions, hypothesis testing person-time data analysis, variance, regression, correlation analysis, epidemiologic studies, death, fertility, morbidity, and statistical applications in bioengineering.
Prerequisite: Graduate Standing
BIOE 511 Design & Use of Biomaterials (3-0-3)
Biomaterials biology and biochemistry fundamentals, properties of materials used in medical applications, classes of materials used in medicine, host reactions involved in biomaterial, biological testing of biomaterials, degradation of materials in the biological systems, applications of materials in medicine and artificial organs, tissue engineering.
Prerequisite: Graduate Standing
BIOE 512 Advanced transport phenomena in Bioengineering (3-0-3)
Transport system in biological system; Transcellular and physiological transport system; Conservation relations for fluid transport, dimensional analysis, and scaling; Fluid flow in the circulation and tissue, Mass transport in biological systems; Mass transport and biochemical interaction, Energy transport in biological system.
Prerequisite: Graduate Standing
BIOE 513 Principles and Applications of Tissue Engineering (3-0-3)
Introduction to tissue engineering, Dynamics of extracellular extraction, Engineering the functional tissue, Bioreactor design, In-vivo synthesis of tissue engineering, Scaffold and biopolymer, Transplantation of cells and tissue, and Stem cells.
Prerequisite: Graduate Standing
BIOE 514 Drug and Gene Delivery (3-0-3)
Principles of controlled release, water solubility of drugs, epithelial barriers, nanotechnologies, and routes for drug delivery and targeting, long-acting injections and implants, transdermal and nasal drug delivery, drug delivery to the central nervous system, gene delivery systems.
Prerequisite: Graduate Standing
BIOE 521 Computational Biomechanics (3-0-3)
Fundamental conservation principles. Fluid dynamics in biological systems. Numerical techniques. Parameter estimation. Finite difference. Numerical integration. Finite element methods. Model physiological functions. Biological system behavior prediction.
Prerequisite: Graduate Standing
BIOE 522 Musculoskeletal Biomechanics (3-0-3)
Foundational understanding of Anatomy and Physiology. Mechanics of muscles, tendons, ligaments, menisci, and Bones. Application of motion equations. Human movement. Analytical and numerical methods of biomechanics. Experimental techniques in biomechanical research.
Prerequisite: Graduate Standing
BIOE 523 Multiscale Biomechanics (3-0-3)
Applying scaling laws and continuum mechanics to biomechanics. Exploring multiple scales from molecules to cells and tissues. Tissue structure and its impact on macroscopic properties. Chemical and electrical effects on mechanical behavior. Cell mechanics and biomembranes. Studying structures at tissue, cellular, and molecular levels using theoretical and experimental techniques.
Prerequisite: Graduate Standing
BIOE 524 Mechanics of Biological Materials (3-0-3)
Studying how bone, cells, and collagen react to forces. Exploring insights into material structure impacting biomechanics. Development of high-performance biomimetic materials.
Prerequisite: Graduate Standing
BIOE 532 Biophotonics (3-0-3)
Overview of Biophotonics. Basic Principles of Light. Optical Fibers for Biophotonics Applications. Fundamentals of Light Sources. Fundamentals of Optical Detectors. Light-Tissue Interactions. Optical Probes and Biosensors. Microscopy. Spectroscopic Methodologies. Optical Imaging Procedures. Biophotonics Technology Applications.
Prerequisite: Graduate Standing
BIOE 533 Biomedical Instrumentation (3-0-3)
Overview of Biomedical Instrumentation. Sensors and Transducers. Signal Filtering and Amplification. Data Acquisition and Signal Processing. Electrocardiography. Electroencephalography. Digital Hearing Aids. Mobile Health, Wearable Health Technology and Wireless Implanted Devices. Safety of Biomedical Instruments and Devices.
Prerequisite: Graduate Standing
BIOE 534 Biosensors (3-0-3)
Introduction to Sensor-Based Measurement Systems. Transducer Technologies. Resistive, Reactance Variation, and Electromagnetic Sensors. Temperature and pressure sensors. Electrochemical and chemical biosensors. Optical sensors. Signal Conditioning. Self-Generating Sensors. Digital and Intelligent Sensors. Miniaturization and Microfabrication. Biosensor Characterization. Bioanalytical Applications. Emerging Trends in Biosensors. Regulatory and Ethical Considerations. Future Directions and Challenges.
Prerequisite: Graduate Standing
BIOE 535 Systems, Signals, and Controls for Bioengineers (3-0-3)
Discrete- and continuous-time signals; basic system properties. Linear time-invariant systems; convolution. Frequency domain analysis; filtering; sampling. Laplace and Fourier transform; transfer functions; poles and zeros; transient and steady-state response. Z-transforms. Dynamic behavior and PID control of first- and second-order processes. Stability. Applications to biological systems, such as central nervous, cognitive, and motor systems.
Prerequisite: Graduate Standing
BIOE 536 Medical Imaging (3-0-3)
Introduction. System Theory. Image Processing. Endoscopy. Microscopy. Magnetic Resonance Imaging. X-ray Imaging. Computed Tomography. X-ray Phase Contrast: Research on a Future Imaging Modality. Emission Tomography. Ultrasound. Optical Coherence Tomography.
Prerequisite: Graduate Standing
BIOE 551 Quality Control in Biotechnology (3-0-3)
Quality control, regulatory affairs, quality assurance, practices, documentation, process validation, ethical considerations, biotechnology operations, biomanufacturing, non-clinical development, clinical development, and project management.
Prerequisite: Graduate Standing
BIOE 553 Environmental Biological Processes (3-0-3)
Microbial growth kinetics, bioenergetics, biological treatment processes, land treatment, suspended-growth, and fixed-film processes, composting, hazardous waste management, and bioremediation.
Prerequisite: Graduate Standing
BIOE 561 Genetics and Genomics (3-0-3)
Human genome, structure, function and variation; clinical cytogenetics, epigenetics and developmental genetics, genetic disorders and genomic medicine; genetic counseling, prenatal screening and diagnosis; ethical issues in genetics and genomics.
Prerequisite: Graduate Standing
BIOE 590 Special Topics in Bioengineering I (3-0-3)
Advanced topics are selected from the broad area of bioengineering. The contents of the course will be provided in detail one semester in advance of that in which it is to be offered.
Prerequisite: Graduate Standing
BIOE 591 Special Topics in Bioengineering II (3-0-3)
Advanced topics are selected from the broad area of bioengineering. The contents of the course will be provided in detail one semester in advance of that in which it is to be offered.
Prerequisite: Graduate Standing
BIOE 692 Special Topics in Bioengineering III (3-0-3)
Advanced topics are selected from the broad area of bioengineering. The contents of the course will be provided in detail one semester in advance of that in which it is to be offered.
Prerequisite: Graduate Standing
BIOE 699 Seminar (1-0-0)
Graduate students are required to attend the seminars by faculty members, visiting scholars, and fellow graduate students. Additionally, each student must present at least one seminar on a timely research topic. Among other things, this course is designed to give the students an overview of research in BIOE, and a familiarity with research methodology, journals, and professional societies in his discipline. Graded on a Pass or Fail basis.
Prerequisite: Graduate Standing
BIOE 701 Directed Research I (0-0-3)
This course is intended to allow Ph.D. students to conduct research-related independent study. The faculty offering the course should submit a research plan to be approved by the BIOE Graduate Program Committee. At the end of the course, the student should submit a report and present his work to the Department Graduate Committee. Graded on a Pass or Fail basis.
Prerequisite: Instructor’s Consent
BIOE 702 Directed Research II (0-0-3)
This course is intended to allow Ph.D. students to conduct research-related independent study. The faculty offering the course should submit a research plan to be approved by the BIOE Graduate Program Committee. At the end of the course, the student should submit a report and present his work to the Department Graduate Committee. Graded on a Pass or Fail basis.
Prerequisite: BIOE 701
BIOE 711 Ph.D. Pre-Dissertation (0-0-3)
This course enables the student to submit his Ph.D. dissertation proposal and defend it in public. The student passes the course if the Ph. D. dissertation committee accepts the submitted dissertation proposal report and upon successfully passing the Dissertation Proposal Public defense.
Prerequisite: Passing the comprehensive exam
BIOE 712 Ph.D. Dissertation (0-0-9)
The student has to undertake and complete a research topic under the supervision of a faculty member in order to probe in depth a specific problem in Bioengineering. Graded on a Pass or Fail basis.
Prerequisite: BIOE 711