BIOE 501: Cellular and Molecular Bioengineering
Cells and Genomes, Cell Chemistry and Bioenergetics, DNA, Chromosomes, and Genomes, DNA Replication, Repair, and Recombination, How Cells Read the Genome: From DNA to Protein, Control of Gene Expression, Principles and Methodology of Recombinant DNA, Membrane Transport of Small Molecules and the Electrical Properties of Membranes, Intracellular Compartments and Protein Sorting, Intracellular Membrane Traffic, Cell Signaling, The Cytoskeleton, Cell Junctions and Extracellular Matrix.
BIOE 502: Anatomy and Physiology for Engineers
Introduction to life, cellular organization and cell division, Introduction to Physiology Anatomy: Description of human primary tissues, Neurons, nerves and nervous systems engineering application, Sensory system (vision, hearing, taste, external and internal sensing), Human bones and skeleton and application, Integumentary system, Muscles and human movement and engineering application, Circulation and Cardiovascular systems engineering application, Kidneys and excretion system and engineering application, Respiratory system and engineering application, Hormones and Endocrine Function, Digestive system, Immune response mechanisms, Reproduction.
BIOE 503: Concepts in Bioengineering
Engineering calculations and conservation laws, bioreactor design and operation, biomechanics, bioinstrumentation, biosensor and biosignals, bioimaging, biomaterials, drug delivery concept, tissue engineering, bioinformatics, regulatory, ethics, and entrepreneurship.
BIOE 504: Statistics for Bioengineers
Basic concept and scope of statistics in our everyday and scientific inquiry, descriptive statistics, data, distribution, variance, and relation, probability, probability variable, probability distribution in life science, hypothesis testing for population mean and variance, hypothesis testing: Person-Time Data, ANOVA testing to compare several treatments, population mode and inferences, simultaneous confidence intervals, ANOVA testing for completely randomized block design and repeated measures design, regression and correlation methods (in biological and diseases-based data), design and analysis techniques for epidemiologic studies, vital statistics for death, fertility, and morbidity ratio.
BIOE 505: Modeling of Biological Systems
Introduction to Computational Modeling in Bioengineering, ODE Models in Biology: Enzyme Kinetics, population dynamics, gene circuits, PDE Models: Diffusion & Transport: Diffusion, heat transfer, tumor growth, wound healing, cardiovascular systems, aerosol drug delivery, and angiogenesis, Reaction–Diffusion & Pattern Formation: Turing patterns, morphogenesis, skin pattern, Stochastic Modeling of Gene Expression: Stochastic process, noise in gene circuits, Biological Networks: Network theory, signaling networks, Agent-Based Modeling (ABM) Basics: Foundations of ABM, agents, environments, population & epidemiology models, Multiscale Modeling: Linking ODE, PDE, and ABM: Multiscale cancer models, scaling up ABMs, Case Studies & Student Projects.
LS542: Biotechnology
Development of Molecular Biotechnology, Production of Recombinant Proteins in Prokaryotic Hosts, Production of Recombinant Proteins in Eukaryotic Hosts, Protein Therapeutics, Recombinant Antibodies, Protein Engineering & Nucleic Acids as Therapeutic Agents, Vaccines, Industrial Uses of Recombinant Microorganisms, Transgenic Plants, Transgenic Animals, Molecular Biotechnology and Society, Quality Control in Biotechnology.
BIOE 511: Design & Use of Biomaterials
Introduction to Materials Science and Engineering, Properties and classification of Biomaterials, Classes of materials used in medicine, Biological chemistry, Biology and Medicine, Biomaterials in tissue interactions (immune response, degradation, sterilization), Biochemical Testing of Biomaterials (or toxicity and biocompatibility), Design & processing of biomaterials (additive manufacturing, coatings, failure modes), Applications of Bio-Materials in Medicine, Biology and artificial organs, Application of Biomaterials in Tissue Engineering, Implants, Devices, and Biomaterials (stents, heart valves, orthopedic implants, drug-eluting systems), New Products and Standards (ASTM/ISO standardization and risk factors).
BIOE 552: Bioprocess and Bioreaction
Cell and cell growth, How Cell Works (Enzyme as protein, amino acid, central dogma, protein synthesis), Enzyme kinetics, Enzyme Immobilization, Bioreactor (classification and choices based on cultivation method), Bioreactor Design - Batch and Continuous Stirred-Tank Reactor (CSTR), Bioreactor consideration in Immobilized Cell system (Active and Passive immobilization, Diffusion), Scale-up of Bioreactors, Operation and Control (Scale-up and its difficulties, Bioreactor Instrumentation and Control, Sterilization process), Recovery and Purification of Product, Applications of Bioreactors (for animal cell culture, tissue engineering, vaccine development, hormone/enzyme engineering, waste water treatment).
BIOE 619: Project
The student will undertake and conduct an industrial research project related to bioengineering under the supervision of a faculty member. Subsequently, the students shall acquire skills and gain experience in developing and running an actual industry-based project. This project culminates in the writing of a technical report and an oral technical presentation in front of a board of professors and industry experts.
Project Requirement:
The culminating experience is an industry-based bioengineering project in which students independently design, execute, and evaluate a real-world research or development problem under faculty supervision. Through this project, students apply advanced theoretical and practical skills, implement appropriate research methodologies, analyze data, and present their findings in both a technical report and an oral presentation before faculty and industry experts, demonstrating mastery of the program’s learning outcomes; including problem solving, research design, communication, and ethical practice.